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, Shapiro, SS, Waknitz, MA, Swiergiel, JJ, Marshall, VS, Jones, JM (1998) Embryonic stem cell lines derived from human blastocysts Science 282: 1145 1147 Vacanti, JP, Langer, R (1999) Tissue engineering: the design and fabrication of living replacement devices for surgical reconstruction and transplantation Lancet 354 Suppl 1: SI32 SI34 Vernon, RB, Lara, SL, Drake, CJ, Iruela-Arispe, ML, Angello, JC, Little, CD, Wight, TN, Sage, EH (1995) Organized type I collagen in uences endothelial patterns during spontaneous angiogenesis in vitro : planar cultures as models of vascular development In Vitro Cell Dev Biol Anim 31: 120 131 Wiles, MV, and Keller, G (1991) Multiple hematopoietic lineages develop from embryonic stem (ES) cells in culture Development 111: 259 267 Williams, RL.

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18 A Brief History of Navigation and Positioning that encountered the same propagation conditions, that is, which was located in the vicinity of the xed reference receiver Using this differential approach, the accuracy dropped down to 15 km, as long as the receiver remained within about 450 km of the xed reference; that is, the propagation conditions remained almost identical The reader should note that this approach was also deployed with the Global Positioning System (GPS) when the US government attached a deliberately generated error, the so-called Selective Availability (which was switched off on May 1, 2000) Besides these global coverage systems, some speci c systems are locally deployed, such as the VOR (VHF Omnidirectional Radio Range) or TACAN (Tactical Air Navigation), as well as others such as ILS (Instrument Landing System) and MLS (Microwave Landing System).

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To make HTML work, you must learn to put block elements within other block elements and to put inline elements into other inline elements and into block elements. This process is called nesting. Consider the following nested list: This is the first bulleted item This is the second bulleted item This is a numbered item This is another numbered item This is a third numbered item This is the third and final bulleted item The following HTML will create the same thing:

, Hilton, DJ, Pease, S, Willson, TA, Stewart, CL, Gearing, DP, Wagner, EF, Metcalf, D, Nicola, NA, Gough, NM (1988) Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells Nature 336: 684 687 Wright, AP, Fitzgerald, JJ, Colello, RJ (1997) Rapid puri cation of glial cells using immunomagnetic separation J Neurosci Methods 74: 37 44 Xu, C, Inokuma, MS, Denham, J, Golds, K, Kundu, P, Gold, JD, Carpenter, MK (2001) Feeder-free growth of undifferentiated human embryonic stem cells Nat Biotechnol 19: 971 974 Xu, RH, Chen, X, Li, DS, Li, R, Addicks, GC, Glennon, C, Zwaka, TP, Thomson, JA.

All these systems were developed for air navigation purposes, in order to provide the locations of aircraft relative to ground facilities The VOR is essentially a rotating radio lighthouse and has a medium distance range The frequency of transmission lies between 108 and 118 MHz, and the signal is modulated in such a way that the transmission is composed of two simultaneous and independent signals at 30 Hz, whose difference of phase characterizes the azimuth of the receiver In order to achieve this, the VOR radiates at a variable 30 Hz with a symmetric radiating diagram exhibiting a cardioid pattern Simultaneously, the second signal is a 30 Hz uniform (omnidirectional pattern) signal whose phase is identical in all directions11 The onboard receiver calculates the direction of the VOR station, but also selects an azimuth route for a direction chosen by a user.

(2002) BMP4 initiates human embryonic stem cell differentiation to trophoblast Nat Biotechnol 20: 1261 1264 Yamashita, J, Itoh, H, Hirashima, M, Ogawa, M, Nishikawa, S, Yurugi, T, Naito, M, Nakao, K (2000) Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors Nature 408: 92 96..

If this direction is the VOR station, then the phase difference signal should be zero Thus, an indication of the deviation between the real route and the VOR station direction can be provided Such equipment could be used for positioning, as long as three VOR stations are in radio visibility, by achieving a triangulation from the three directions of arrival measurements As a matter of fact, this system is mainly used as an alignment device and is usually associated with DME (Distance Measuring Equipment), which gives the distance between the device and a reference ground station An association between VOR and DME thus gives the plane s location (in polar coordinates) in the ground station referential The range is typically 200 miles in good conditions and the accuracy lies around 02 miles or 025% of the measured distance.

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